| Yazarlar (5) |
Prof. Dr. Kemal ÖRNEK
Kırşehir Ahi Evran Üniversitesi, Türkiye |
Emine Temel
Kırşehir Ahi Evran Üniversitesi, Türkiye |
|
Gökçen Özcan
Kırşehir Ahi Evran Üniversitesi, Türkiye |
Doç. Dr. Özkan KOCAMIŞ
Kırşehir Ahi Evran Üniversitesi, Türkiye |
|
Nazife Aşıkgarip
Kırşehir Ahi Evran Üniversitesi, Türkiye |
| Özet |
| Dear Editor, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly pathogenic human coronavirus that can cause serious life-threatening respiratory disease and multiorgan failure (1). Despite the swift global spread of coronavirus disease 19 (COVID-19), no reliable clinical data are available to endorse any specific medical therapy. Organ-supportive therapy, including respiratory therapy, in acute pulmonary failure is recommended by physicians worldwide. For supportive management, hydroxychloroquine sulfate (HCQ) is being widely used. Retinal toxicity is a well-known adverse effect of HCQ. It is generally irreversible and can worsen even after treatment is discontinued. Although no clear evidence of retinal toxicity has been found in patients with COVID-19, screening for HCQ-related retinal adverse effects has been a major concern throughout the pandemic. We assessed short-term changes in the ganglion cell complex (GCC)-the retinal nerve fiber layer, the ganglion cell layer and the inner plexiform layer-by using spectral-domain optical coherence tomography (SD-OCT) in patients with COVID-19 who were treated with HCQ. We studied the eyes of 40 patients with moderate type COVID-19 (Group 1) and the eyes of 40 healthy participants (Group 2). All the patients had tested positive for SARS-CoV-2 by real-time reverse transcriptase polymerase chain reaction. The protocol was performed in adherence to the tenets of the Declaration of Helsinki and was approved by the institutional review board of Kırşehir Ahi Evran University. For the measurement, an area 3000 μm wide with a 1500-μm margin nasal to the fovea … |
| Anahtar Kelimeler |
| Makale Türü | Diğer (Teknik, not, yorum, vaka takdimi, editöre mektup, özet, kitap krıtiği, araştırma notu, bilirkişi raporu ve benzeri) |
| Makale Alt Türü | SCI, SSCI, AHCI, SCI-Exp dergilerinde yayınlanan teknik not, editöre mektup, tartışma, vaka takdimi ve özet türünden makale |
| Dergi Adı | ARQUIVOS BRASILEIROS DE OFTALMOLOGIA |
| Dergi ISSN | 0004-2749 Wos Dergi Scopus Dergi |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Makale Dili | Türkçe |
| Basım Tarihi | 01-2021 |
| Cilt No | 84 |
| Sayı | 4 |
| Sayfalar | 408 / 409 |
| Doi Numarası | 10.5935/0004-2749.202100107 |
| Atıf Sayıları | |
| Google Scholar | 2 |
