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Choroidal vascularity index after a single dose of intravitreal dexamethasone implant in patients with refractory diabetic macular edema       
Yazarlar
Doç. Dr. Özkan KOCAMIŞ
Kırşehir Ahi Evran Üniversitesi, Türkiye
Emine Temel
Türkiye
Gökçen Özcan
Türkiye
Nazife Aşıkgarip
Türkiye
Prof. Dr. Kemal ÖRNEK
Kırşehir Ahi Evran Üniversitesi, Türkiye
Özet
Purpose: To evaluate choroidal vascularity index (CVI) after a single dose of intravitreal dexamethasone implant in refractory diabetic macular oedema (DME). Methods: Total choroidal area, luminal area, and CVI were measured at baseline, 1st month, and at 3rd month after dexamethasone implant using binarization of enhanced depth imaging optical coherence tomography (EDI-OCT) images. Results: A total of 25 eyes of 25 patients (mean age: 61.4 +/- 8.3 years; 12 males, 13 females), were enroled in the study. All eyes had been previously treated with intravitreal aflibercept injections (mean number of injections 4.6 +/- 2.5). Mean CVI was 70.3 +/- 8.1 prior to intravitreal dexamethasone treatment. It was decreased to 66.1 +/- 9.3 at 1 month and 63.5 & PLUSMN; 10.1 at 3 months after treatment. The mean CVI was significantly decreased at 3 months compared with pre-treatment measures (p = 0.033). Conclusion: CVI was found to be decreased in patients who responded to intravitreal dexamethasone implant.
Anahtar Kelimeler
Aflibercept, Choroidal vascularity index, Dexamethasone, Diabetic macular oedema, Enhanced depth -optical coherence tomography
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı Photodiagnosis and Photodynamic Therapy
Dergi ISSN 1572-1000
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q3
Makale Dili İngilizce
Basım Tarihi 01-2022
Makale Linki https://www.sciencedirect.com/science/article/abs/pii/S1572100022002824?via%3Dihub
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
WoS 1
Google Scholar 2

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