| Yazarlar (3) |
İnci Elif Erbahçeci Timur
Türkiye |
Prof. Dr. Kemal ÖRNEK
Kırşehir Ahi Evran Üniversitesi, Türkiye |
|
Osman Çağlayan
Kırıkkale Üniversitesi, Türkiye |
| Özet |
| Aim: To determine the association between serum and aqueous apolipoprotein (Apo) A1 and Apo B levels and Apo B/A1 ratio in diabetic retinopathy. Material and Method: This cross-sectional prospective study included 63 diabetic patients with or without retinopathy and 38 control subjects who underwent cataract surgery. The study groups were as follows; healthy subjects (Group 1), diabetic patients without retinopathy (Group 2), with non-proliferative diabetic retinopathy (Group 3), and with proliferative diabetic retinopathy (Group 4). Serum and aqueous Apo A1 and Apo B levels were determined by using an enzyme-linked immunosorbent assay. Results: The amount of Apo B was determined in aqueous samples of all (100%) patients in Group 4 and 77.7% of patients in Group 3.The mean serum Apo B/A1 ratio was significantly higher in Group 2, Group 3 and Group 4 compared with Group 1 (p=0.002, p=0.037 and p<0.001, respectively). The aqueous Apo B level, aqueous and serum Apo B/A1 levels were significantly correlated with the severity of retinopathy in diabetic patients (all p<0.001). Conclusion: Higher serum and aqueous Apo B/A1 ratio were significantly associated with the stage of diabetic retinopathy. |
| Anahtar Kelimeler |
| Makale Türü |
Özgün Makale
|
| Makale Alt Türü | Ulusal alan endekslerinde (TR Dizin, ULAKBİM) yayınlanan tam makale |
| Dergi Adı | Journal of health sciences and medicine (Online) |
| Dergi ISSN | 2636-8579 |
| Dergi Tarandığı Indeksler | ULAKBİM TR Dizin, Index Copernicus, ICI World of Journals, DOAJ, Directory of Research Journals Indexing (DRJI), General Impact Factor, ASOS Index, WorldCat (OCLC), MIAR, EuroPub, OpenAIRE, Türkiye Citation Index, Türk Medline Index, InfoBase Index, Scilit. |
| Makale Dili | İngilizce |
| Basım Tarihi | 03-2023 |
| Cilt No | 6 |
| Sayı | 2 |
| Sayfalar | 546 / 551 |
| Doi Numarası | 10.32322/jhsm.1253299 |
| Atıf Sayıları |
