| Yazarlar (3) |
İltifat Abdulrezzaq Jawad Alsahlanee
|
Dr. Öğr. Üyesi İsmail BAYRAM
Kırşehir Ahi Evran Üniversitesi, Türkiye |
|
Lames Majid Hameed Al-Janabi
|
| Özet |
| Matrilin-3 is a protein found in the extracellular matrix that is not composed of collagen. The MATN3 gene is found on the short arm of chromosome 2 region 2p24-p23. Matn3 is found at lower levels in mature articular cartilage (AC), but its expression is induced through (OA), This pattern of expression indicates that Matrilin-3 has a role in the etiology of osteoarthritis. Some studies have found that mutations in the MATN3 gene area are a risk factor for OA. this study aimed to examine the association of the Matn3 (rs77245812) SNP(C/T) gene polymorphism as a risk factor for osteoarthritis. genotyping of the SNP(C/T) was performed in 50 type2 diabetes with osteoarthritis, 50 osteoarthritis, and 50 control subjects. Genomic DNA was isolated from venous blood samples, quantified, and subjected to conventional PCR. statistical analysis showed no association found between Matn3 (rs77245812) and the risk … |
| Anahtar Kelimeler |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SCOPUS dergilerinde yayınlanan tam makale |
| Dergi Adı | Natural Volatiles& Essentiol Oils |
| Dergi ISSN | 2148-9637 Scopus Dergi |
| Dergi Tarandığı Indeksler | Scopus |
| Makale Dili | İngilizce |
| Basım Tarihi | 01-2022 |
| Cilt No | 9 |
| Sayı | 1 |
| Sayfalar | 1321 / 1330 |
| Makale Linki | https://www.nveo.org/index.php/journal/article/view/4740 |
