| Yazarlar |
Sıddıka Fındık
Necmettin Erbakan Üniversitesi, Türkiye |
|
Serkan Fındık
|
|
Seyfettin Abuoğlu
|
|
Fatma Goksin Cihan
|
Dr. Öğr. Üyesi Hüseyin İLTER
Türkiye |
|
Mehmet Sinan İyisoy
Necmettin Erbakan Üniversitesi, Türkiye |
| Özet |
| Objective: Cervical cancer can be diagnosed early by cancer screening programs. The aim of this study was to evaluate the cervical smear test results of healthy women. Methods: We enrolled 94,848 healthy women from 30-65 years of age in whom both HPV typing and a cervical smear test was performed between 2014 and 2017. Results: HPV was detected in 3001 women (3.16%). The mean age was 42 +/- 8.94 years old. Positive HPV types were HPV16; HPV16 and multiple infection; HPV31; HPV51; HPV39; HPV52; HPV56; HPV18; HPV68; HPV35; HPV18 and multiple infection; HPV58; HPV45; HPV59; HPV16, HPV18 and multiple infection; HPV16 and 18; and HPV33, in descending order. Cytology results were normal in 63.61%. We also identified atypical squamous cells of undetermined significance in 6.60%, atypical squamous cells-cannot exclude high-grade squamous intraepithelial lesion in 0.73%, low-grade squamous intraepithelial lesion in 10%, high-grade squamous intraepithelial lesion and atypical glandular cells in 0.53%, and adenocarcinoma in situ in 0.03%. In terms of HPV subtypes, abnormal smear results were divided into an HPV16, HPV18, and multiple infection group (25%), an HPV35 group (23.61%), an HPV 16 and multiple infection group (22%), and an HPV16-only group (21.85%). Most cases of HPV (39.02%) and abnormal cytology (43.04%) were detected between the ages of 30 and 40. Conclusions: This study is remarkable because it is a community-based study and includes a large population of healthy women to detect HPV prevalence, its subtype, and abnormal smear results. |
| Anahtar Kelimeler |
| Papanicolaou test, human papilloma virus, primary care, screening |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | International Journal of Clinical and Experimental Pathology |
| Dergi ISSN | 1936-2625 |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Makale Dili | İngilizce |
| Basım Tarihi | 04-2019 |
| Cilt No | 12 |
| Sayı | 4 |
| Sayfalar | 1391 / 1398 |
