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Nanospheres caped Pt(II) and Pt (IV): synthesis and evaluation as antimicrobial and Antifungal Agent    
Yazarlar
Prof. Dr. Hatice ÖĞÜTCÜ Prof. Dr. Hatice ÖĞÜTCÜ
Ahi Evran Üniversitesi, Türkiye
Nurdan Kurnaz Yetim
Kırklareli Üniversitesi, Türkiye
Elvan Hasanoğlu Özkan
Orçun Eren
Gamze Kaya
Nurşen Sarı
Gazi Üniversitesi, Türkiye
Ali Dişli
Gazi Üniversitesi, Türkiye
Özet
Antimicrobial and antifungal polymers are gaining the attention of pharmaceutical makers and industrial design. Nanospheres-Polymers attached Platinum(II) / (IV) complexes have been synthesized to investigate antimicrobial activities. Firstly, nanospheres involving Schiff bases were synthesized from (aminomethyl) polystyrene and four substitute salicylaldehyde (2-hydroxy benzaldehyde, 5-fluoro-2-hydroxy benzaldehyde, 5-kloro-2-hydroxy benzaldehyde, 5-bromo-2-hydroxy benzaldehyde). Secondly, polymers attached Platinum(II) / (IV) complexes have been prepared by means of template method. The IR spectra show that the ligands act in a monovalent bidentate fashion all nanospheres involving Schiff bases. Square-planar and octahedral structures are proposed for Pt(II) and Pt(IV), respectively. All these substances have been examined for antibacterial activity against pathogenic strains, and antifungal activity. In particular, Pt(IV) complexes were more potent bactericides than all of the synthesized substances.
Anahtar Kelimeler
antimicrobial agent | antifungal agent | poly(styrene) | caped platinium
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı POLISH JOURNAL OF CHEMICAL TECHNOLOGY
Dergi ISSN 1509-8117
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce
Basım Tarihi 03-2017
Cilt No 19
Sayı 1
Sayfalar 74 / 80
Doi Numarası 10.1515/pjct-2017-0011
Makale Linki http://dx.doi.org/10.1515/pjct-2017-0011