Synthesis, Characterization and Antimicrobial Activities of Novel Double-Armed Benzo-15-Crown-5 and Their Sodium and Potassium Complexes
   
Yazarlar (3)
Öznur Şener Cemaloğlu
Ankara University, Türkiye
Prof. Dr. Hatice ÖĞÜTCÜ Kırşehir Ahi Evran Üniversitesi, Türkiye
Zeliha Hayvalı
Ankara Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı JOURNAL OF CHEMICAL RESEARCH
Dergi ISSN 1747-5198 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI
Makale Dili Türkçe Basım Tarihi 01-2021
Cilt / Sayı / Sayfa 45 / 1 / 116–124 DOI 10.1177/1747519820932264
Makale Linki http://www.elsevier.com/locate/molstruc
Özet
New aldehyde- and halogen- (Cl, Br, I) substituted double-armed benzo-15-crown-5 derivatives are synthesized by the reactions of 4 ',5 '-bis(bromomethyl)benzo-15-crown-5 with 5-chlorosalicylaldehyde, 5-bromosalicylaldehyde, or 5-iodosalicylaldehyde. The sodium and potassium complexes are obtained by reaction of crown ether with sodium perchlorate and potassium iodide, respectively. Novel Schiff base compounds containing three groups of benzo-15-crown-5 are obtained from the condensation of aldehydes with 4 '-aminobenzo-15-crown-5. The structures of all compounds are elucidated by elemental analysis,H-1,C-13 NMR, IR, and mass spectra. The antifungal and antibacterial effects of the synthesized ligands are evaluated against pathogenic microorganisms and show varying degrees of inhibitory effects against the growth of different pathogenic strains. Graphical abstract
Anahtar Kelimeler
alkali metal complexes | antimicrobial activity | crown ethers | pathogenic microorganisms | Schiff bases