Yazarlar |
Volkan Yanmaz
|
Ali Dişli
Gazi Üniversitesi, Türkiye |
Serkan Yavuz
Gazi Üniversitesi, Türkiye |
Prof. Dr. Hatice ÖĞÜTCÜ
Kırşehir Ahi Evran Üniversitesi, Türkiye |
Gülay Dilek
Zonguldak Bülent Ecevit Üniversitesi, Türkiye |
Özet |
A series of novel substituted isoxazolidine derivatives were synthesized by 1,3-dipolarcycloaddition reactions of α-aryl-N-methyl nitrones with diethyl maleate. The structures of thesynthesized compounds were characterized using spectroscopic methods. All the synthesizedcompounds were screened for their antibacterial activities against Gram-positive and Gramnegativebacteria and for their antifungal activities against a yeast strain. The results show that allthe synthesized compounds displayed significant activity against S. epidermidis, M. luteus, B.cereus, B. abortus and C. albicans when compared to standard drugs. |
Anahtar Kelimeler |
Isoxazolidine | Nitrone | 1,3-Dipolar cycloaddition reaction | Antimicrobial activity |
Makale Türü | Özgün Makale |
Makale Alt Türü | ESCI dergilerinde yayımlanan tam makale |
Dergi Adı | GAZI UNIVERSITY JOURNAL OF SCIENCE |
Dergi ISSN | 2147-1762 |
Dergi Tarandığı Indeksler | TR DİZİN |
Makale Dili | Türkçe |
Basım Tarihi | 01-2019 |
Cilt No | 32 |
Sayı | 1 |
Sayfalar | 78 / 89 |