| Yazarlar |
Serhat Koçoğlu
Başkent Üniversitesi, Türkiye |
Prof. Dr. Hatice ÖĞÜTCÜ
Kırşehir Ahi Evran Üniversitesi, Türkiye |
|
Zeliha Hayvalı
Ankara Üniversitesi, Türkiye |
| Özet |
| Nitropyridine substituted double-armed benzo 15-crown-5 compounds (1-4) were synthesized by the reactions of 4',5'-bis(bromomethyl)benzo-15-crown-5 with hydroxypyridine derivatives. Na+ and K+ complexes (1a-4a, 1b-4b) of crown ether compounds (1-4) were prepared with sodium picrate and potassium picrate, respectively. Transition metal complexes (1c-4c) of the synthesized ligands (1-4) were prepared from Ag+ cation. In addition, nitro compounds (1, 2 and 4) were reduced by using Pd/C and hydrazine hydrate and new amine compounds (5, 6 and 8) were obtained. The structures of new double-armed crown ether compounds (2-4), their metal complexes (1a-4a, 1b-4b, 2c-4c) and amine compounds (5, 6 and 8) were elucidated by FTIR, HRMS, H-1-NMR, C-13-NMR spectroscopic methods. The thermal behaviors of these nitro group containing ligands (1-4) were compared with the resulting silver complexes (1c-4c) and amine compounds (5, 6 and 8). All synthesized compounds were examined for antibacterial activity against pathogenic strains Listeria monocytogenes, Salmonella typhi H, Bacillus cereus, Staphylococcus aureus, Staphylococcus epidermidis, Micrococcus luteus, Escherichia coli, Klebsiella pneumonia, Proteus vulgaris, Serratia marcescens, Shigella dysenteria and antifungal activity against Candida albicans. |
| Anahtar Kelimeler |
| Crown ethers | Pyridine compounds | Alkali metal complexes | Transition metal complexes | Antimicrobial activity | Thermal analysis |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | Journal of Inclusion Phenomena and Macrocyclic Chemistry |
| Dergi ISSN | 1388-3127 |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q3 |
| Makale Dili | İngilizce |
| Basım Tarihi | 01-2022 |
| Cilt No | 102 |
| Sayı | 9 |
| Sayfalar | 763 / 780 |
| Doi Numarası | 10.1007/s10847-022-01157-y |
| Makale Linki | https://suggestor.step.scopus.com/progressTracker/?trackingID=50D4F05A17EBE87D%20 |
| Atıf Sayıları |
