Effect of Lipoic Acid on the Some Elements in Brain Tissue ofDMBA Induced Guinea Pigs
Yazarlar (7)
Prof. Dr. Harun ÇİFTÇİ Kırşehir Ahi Evran Üniversitesi, Türkiye
Ahmet Özkaya Adıyaman Üniversitesi, Türkiye
Alpaslan Dayangaç Ahi Evran Üniversitesi, Türkiye
Ali Ölçücü Fırat Üniversitesi, Türkiye
Sait Çelik
Uşak Üniversitesi, Türkiye
Uşak Üniversitesi, Türkiye
Zafer Şahin Firat Üniversitesi, Türkiye
Sema Ateş Firat Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Kafkas Universitesi Veteriner Fakultesi Dergisi | ||
| Dergi ISSN | 1300-6045 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 01-2009 |
| Cilt / Sayı / Sayfa | 15 / 4 / 569–573 | DOI | 10.9775/kvfd.2009.067-a |
| Özet |
| This study was conducted to determine the antioxidant properties of lipoic acid in guineapigs. 7,12-dimethylbenz-[a]anthracene (DMBA) was administered to guineapigs. The α-lipoic acid (a-LA) antioxidant properties against the levels of macro and trace elements in brain were analysed. 24 adult male guineapigs were randomly divided into four equal groups (control, DMBA, a-LA and DMBA+aLA). Results revealed that the level of calcium from macroelements in DMBA treated group increased (P<0.01) and decreased in DMBA+a-LA group (P<0.01) when compared with the control group. Magnesium decreased in DMBA group (P<0.01) and DMBA+a-LA group, and increased in the control group. It was observed that copper levels decreased in DMBA (P<0.01) and DMBA+a-LA groups. The zinc level decreased in DMBA group (P<0.01) and increased in DMBA+a-LA group (P<0.01). It was observed that the … |
| Anahtar Kelimeler |
| 7,12-dimetilbenz-[a]antrasen | Brain | DMBA | Guinea pig | ICP-AES | Trace Element | α-Lipoic acid |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Google Scholar | 14 |
| Scopus | 7 |
| Web of Science | 7 |