Synthesis, Characterization and Glutathione Reductase Inhibitors studies of dinuclear copper (II) complexes
Proje Ekibi (1)
| Proje Türü | Yükseköğretim Kurumları Tarafından Destekli Bilimsel Araştırma Projesi |
| Proje No | MMF.E2.16.003 |
| Proje Sahibi Kurum | Kırşehir Ahi Evran Üniversitesi |
| Proje Durumu | Tamamlandı |
| Başlangıç Tarihi | 05-05-2016 |
| Bitiş Tarihi | 26-07-2016 |
| Proje Konusu | Three dinuclear copper (II) complexes (1, 2 and 3) of chiral Schiff bases prepared by reaction of o-hydroxybenzaldehyde and chiral amino alcohols (S)-(+)-phenylglycinol, (1S, 2R)-2-amino-1,2-diphenylethanol, and (R)-(+)-2-amino-1,1,3-triphenylpropanol have been synthesized and characterizated by using elemental analyses, FTIR, LCMS, magnetic susceptibility and conductivity measurement techniques. These compounds were examined for effects on glutathione reductase. The best inhibitory effect has been shown to complex 3. |
